Calcium entry induced by acetylcholine action on snail neurons.
نویسندگان
چکیده
A study was made of excitatory and inhibitory responses elicited by acetylcholine (ACh) in neurons of the snail Eobania vermiculata. At resting potential, ACh evoked a depolarizing inward current in some neurons (D-cells) and a hyperpolarizing current in others (H-cells). The currents elicited by ACh were nonlinearly dependent on membrane potential. After either D- or H-cells were equilibrated in chloride-free isotonic calcium, ACh evoked a depolarizing inward current which reversed sign at about -55 mV. These results suggest that ACh causes an influx of Ca2+ in both types of neurons.
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عنوان ژورنال:
- Proceedings of the Royal Society of London. Series B, Biological sciences
دوره 225 1238 شماره
صفحات -
تاریخ انتشار 1985